El Radaman Y Su Dieta
Enviado por antons7 • 30 de Septiembre de 2012 • 5.929 Palabras (24 Páginas) • 379 Visitas
Kidney Diseases
Iranian Journal of Kidney Diseases | Volume 6 | Number 1 | January 2012 33
Original Paper
Effect of Ramadan Fasting on Urinary Risk Factors for
Calculus Formation
Amir Hossein Miladipour,1 Nasser Shakhssalim,2 Mahmoud Parvin,2
Mohaddeseh Azadvari3
Introduction. Even though dehydration could aggravate formation
of urinary calculi, the effects of fluid and food restriction on calculus
formation is not thoroughly defined. The purpose of this study
is to evaluate the effects of fluid and food restriction in Ramadan
fasting on urinary factors in kidney and urinary calculus formation.
Materials and Methods. Fifty-seven men aged 30 to 55 years old,
including 37 recurrent calcium calculus formers and 20 with no history
of kidney calculi were evaluated for blood tests, ultrasonography
investigations, urinalysis, urine culture, and also 24-hour urine
collection test. Urinary metabolites including calcium, oxalate,
citrate, uric acid, magnesium, phosphate, potassium, sodium, and
creatinine were measured before and during Ramadan fasting.
The values of calculus-precipitating solutes as well as inhibitory
factors were documented thoroughly.
Results. Total excretion of calcium, phosphate, and magnesium in
24-hour urine and also urine volume during fasting were significantly
lower than those in the nonfasting period. Urine concentration of
calcium during fasting was significantly lower than nonfasting
(P < .001). Urine concentrations of uric acid, citrate, phosphate,
sodium, and potassium during fasting were significantly higher
than nonfasting. Uric acid supersaturation was accentuated, and
calcium phosphate supersaturation was decreased significantly
during fasting. There was no significant increase in calcium oxalate
supersaturation during the fasting period.
Conclusions. Fasting during Ramadan has different effects on total
excretion and concentrations of urinary precipitate and inhibitory
factors contributing to calculus formation. We did not find enough
evidence in favor of increased risks of calculus formation during
Ramadan fasting.
IJKD 2012;6:33-8
www.ijkd.org
1Urology and Nephrology
Research Center, Shohada-e-
Tajrish Medical Center, Shahid
Beheshti University of Medical
Sciences, Tehran, Iran
2Urology and Nephrology
Research Center, Shahid
Labbafinejad Medical Center,
Shahid Beheshti University of
Medical Sciences, Tehran, Iran
3Urology and Nephrology
Research Center, Shahid
Beheshti University of Medical
Sciences, Tehran, Iran
Keywords. fasting, urolithiasis,
risk factors
INTRODUCTION
Urinary calculus formation is a common
troublesome and costly urinary system disorder.
Even though dehydration could aggravate the
process of calculus formation throughout the kidney
and urinary outgoing system, the effect of total
abstention from food and water during the month
of Ramadan is unclear. Every year during Ramadan
month, fasting is practiced by Muslims throughout
the world. During Ramadan, the osmolarity of the
urine samples collected, especially in the afternoon
become very high (mean, 849 mOsm/kg to 937
mOsm/kg).1 Not only is the eating pattern greatly
altered during the Ramadan period, but also the
Fasting and Urinary Risk Factors—Miladipour et al
34 Iranian Journal of Kidney Diseases | Volume 6 | Number 1 | January 2012
amount and type of food eaten during the night
may also be significantly different to that usually
consumed during the rest of the year. Moreover,
there is dehydration during the daylight hours of
Ramadan fasting; thus, it seems to be intermittent
dehydration.2
To date, only limited studies have been conducted
about the effect of Ramadan fasting on urinary
calculus formation. This study was designed to
evaluate the effects of fasting during Ramadan
on urinary precipitating and inhibitory factors of
calculus formation.
MATERIALS AND METHODS
We evaluated 57 men aged 30 to 55 years old.
They
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